INT261413

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Context Info
Confidence 0.00
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.81
Pain Relevance 0.77

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Creb1) nucleus (Creb1) plasma membrane (GRIN1)
DNA binding (Creb1) transcription factor binding (Creb1)
GRIN1 (Homo sapiens)
Creb1 (Mus musculus)
Pain Link Frequency Relevance Heat
nMDA receptor 66 100.00 Very High Very High Very High
Anterior cingulate cortex 19 99.68 Very High Very High Very High
long-term potentiation 57 76.64 Quite High
Lasting pain 20 74.00 Quite High
antagonist 18 66.20 Quite High
Acute pain 1 63.52 Quite High
Inflammation 4 60.88 Quite High
allodynia 2 47.88 Quite Low
Neuropathic pain 1 18.72 Low Low
painful pain 1 18.60 Low Low
Disease Link Frequency Relevance Heat
Injury 10 98.40 Very High Very High Very High
Targeted Disruption 7 90.48 High High
Pain 26 74.00 Quite High
INFLAMMATION 4 60.88 Quite High
Neuropathic Pain 3 47.88 Quite Low
Nervous System Injury 4 8.08 Low Low
Anxiety Disorder 21 5.00 Very Low Very Low Very Low
Amnesia 2 5.00 Very Low Very Low Very Low
Brain Disease 2 5.00 Very Low Very Low Very Low
Depression 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The activation of NMDA receptors triggers postsynaptic calcium, leading to the activation of calcium-stimulated CREB in the ACC after peripheral or central injury [42] (see Figure 4).


Positive_regulation (activation) of NMDA Positive_regulation (leading) of Positive_regulation (activation) of CREB associated with nmda receptor, injury and anterior cingulate cortex
1) Confidence 0.00 Published 2009 Journal Mol Brain Section Body Doc Link PMC2644299 Disease Relevance 0.81 Pain Relevance 0.77

General Comments

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