INT261447

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.77

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Akr1d1) extracellular space (Sftpd) oxidoreductase activity (Akr1d1)
extracellular region (Sftpd) cytoplasm (Akr1d1)
Anatomy Link Frequency
neuronal 1
Sftpd (Rattus norvegicus)
Akr1d1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Nucleus accumbens 17 97.56 Very High Very High Very High
Glutamate 2 97.24 Very High Very High Very High
Pyramidal cell 1 95.24 Very High Very High Very High
Dopamine 62 82.40 Quite High
Ventral tegmentum 13 79.76 Quite High
agonist 14 73.56 Quite High
antagonist 8 67.68 Quite High
Central nervous system 7 59.12 Quite High
Substantia nigra 9 5.00 Very Low Very Low Very Low
ischemia 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 28 5.00 Very Low Very Low Very Low
Schizophrenia 25 5.00 Very Low Very Low Very Low
Hypertension 9 5.00 Very Low Very Low Very Low
Injury 4 5.00 Very Low Very Low Very Low
Attention Deficit Hyperactivity Disorder 4 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 4 5.00 Very Low Very Low Very Low
Cognitive Disorder 3 5.00 Very Low Very Low Very Low
Depression 3 5.00 Very Low Very Low Very Low
Natriuresis 2 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, it is possible that SPD directly activates D1 receptors on mPFC glutamatergic neurons that project to the NAc, thus indirectly influencing neuronal activity in the NAc.
SPD Positive_regulation (activates) of D1 in neuronal associated with nucleus accumbens
1) Confidence 0.01 Published 2007 Journal Current Neuropharmacology Section Body Doc Link PMC2644490 Disease Relevance 0 Pain Relevance 0.77

General Comments

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