INT261460

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.43
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Akr1d1) extracellular space (Sftpd) oxidoreductase activity (Akr1d1)
extracellular region (Sftpd) cytoplasm (Akr1d1)
Sftpd (Rattus norvegicus)
Akr1d1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dopamine 62 93.56 High High
Substantia nigra 9 69.60 Quite High
Nucleus accumbens 17 5.00 Very Low Very Low Very Low
agonist 14 5.00 Very Low Very Low Very Low
Ventral tegmentum 13 5.00 Very Low Very Low Very Low
antagonist 8 5.00 Very Low Very Low Very Low
Central nervous system 7 5.00 Very Low Very Low Very Low
ischemia 4 5.00 Very Low Very Low Very Low
depression 3 5.00 Very Low Very Low Very Low
noradrenaline 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Schizophrenia 25 99.04 Very High Very High Very High
Disease 28 85.36 High High
Hypertension 9 5.00 Very Low Very Low Very Low
Injury 4 5.00 Very Low Very Low Very Low
Attention Deficit Hyperactivity Disorder 4 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 4 5.00 Very Low Very Low Very Low
Cognitive Disorder 3 5.00 Very Low Very Low Very Low
Depression 3 5.00 Very Low Very Low Very Low
Natriuresis 2 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These unique dual effects have suggested that SPD can effectively restore previously imbalanced functional linkage between D1 and D2 receptors under schizophrenic conditions, in which, SPD improves both the negative and positive symptoms of schizophrenia.
SPD Binding (linkage) of D1 associated with schizophrenia
1) Confidence 0.01 Published 2007 Journal Current Neuropharmacology Section Abstract Doc Link PMC2644490 Disease Relevance 0.43 Pain Relevance 0.16

General Comments

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