INT261478

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Context Info
Confidence 0.10
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.23
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Ephb1, Egr1) endosome (Ephb1) signal transduction (Ephb1)
nucleus (Egr1) intracellular (Egr1) plasma membrane (Ephb1)
Ephb1 (Rattus norvegicus)
Egr1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
long-term potentiation 6 100.00 Very High Very High Very High
insula 1 96.48 Very High Very High Very High
amygdala 2 96.16 Very High Very High Very High
Hippocampus 4 93.96 High High
Glutamate 4 80.96 Quite High
Pain 24 50.00 Quite Low
Nerve growth factor 7 38.20 Quite Low
qutenza 1 13.68 Low Low
Spinal cord 22 5.00 Very Low Very Low Very Low
Inflammation 20 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aids-related Complex 1 99.80 Very High Very High Very High
Disease 2 64.92 Quite High
Neurodegenerative Disease 1 63.12 Quite High
Pain 25 50.00 Quite Low
Apoptosis 3 48.04 Quite Low
Nociception 8 17.92 Low Low
INFLAMMATION 16 5.00 Very Low Very Low Very Low
Neuropathic Pain 16 5.00 Very Low Very Low Very Low
Spinal Cord Injury 8 5.00 Very Low Very Low Very Low
Injury 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In a general way, ERK activation seems to contribute to LTP by controlling the expression of genes such as zif268 and arc [88, 113].
Positive_regulation (activation) of ERK Regulation (controlling) of Gene_expression (expression) of zif268 associated with aids-related complex and long-term potentiation
1) Confidence 0.10 Published 2007 Journal Current Neuropharmacology Section Body Doc Link PMC2644492 Disease Relevance 0.23 Pain Relevance 0.55

General Comments

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