INT261480

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Context Info
Confidence 0.04
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.80
Pain Relevance 0.84

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Ephb1) signal transduction (Ephb1) nucleolus (Trib3)
plasma membrane (Ephb1) nucleus (Trib3) enzyme binding (Trib3)
Trib3 (Rattus norvegicus)
Ephb1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Pain 24 97.08 Very High Very High Very High
Lasting pain 4 92.88 High High
Hyperalgesia 5 87.60 High High
allodynia 7 86.92 High High
intrathecal 7 82.88 Quite High
Inflammation 20 79.28 Quite High
Central nervous system 3 77.68 Quite High
Intracerebroventricular 1 68.64 Quite High
Spinal cord 22 62.76 Quite High
Neuronal excitability 1 35.24 Quite Low
Disease Link Frequency Relevance Heat
Pain 25 97.08 Very High Very High Very High
Hyperalgesia 5 87.60 High High
Neuropathic Pain 16 86.92 High High
INFLAMMATION 16 79.28 Quite High
Nociception 8 75.68 Quite High
Hypersensitivity 3 28.00 Quite Low
Spinal Cord Injury 8 5.00 Very Low Very Low Very Low
Injury 6 5.00 Very Low Very Low Very Low
Arthritis 4 5.00 Very Low Very Low Very Low
Apoptosis 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The most commonly used strategy to prevent ERK activation is by blocking the activation of ERK by its upstream kinase MEK (Fig. 4).
Negative_regulation (blocking) of kinase Positive_regulation (activation) of ERK
1) Confidence 0.04 Published 2007 Journal Current Neuropharmacology Section Body Doc Link PMC2644492 Disease Relevance 0.80 Pain Relevance 0.84

General Comments

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