INT261495

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Context Info
Confidence 0.29
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.21
Pain Relevance 0.57

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Bdnf, Bdnf) cytoplasmic membrane-bounded vesicle (Bdnf, Bdnf) endosome (Ephb1)
signal transduction (Ephb1) plasma membrane (Ephb1) cytoplasm (Ephb1)
Anatomy Link Frequency
spinal 3
Bdnf (Rattus norvegicus)
Bdnf (Rattus norvegicus)
Ephb1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Glutamate receptor 1 99.24 Very High Very High Very High
Spinal cord 22 96.16 Very High Very High Very High
substance P 5 95.36 Very High Very High Very High
Pain 24 86.84 High High
Glutamate 4 83.96 Quite High
bradykinin 1 72.20 Quite High
Inflammation 20 69.76 Quite High
Kinase C 3 69.12 Quite High
Neuropathic pain 8 55.80 Quite High
intrathecal 7 41.84 Quite Low
Disease Link Frequency Relevance Heat
Pain 25 86.84 High High
INFLAMMATION 16 69.76 Quite High
Neuropathic Pain 16 55.80 Quite High
Spinal Cord Injury 8 21.12 Low Low
Urological Neuroanatomy 1 20.96 Low Low
Cystitis 2 16.48 Low Low
Nociception 8 5.00 Very Low Very Low Very Low
Injury 6 5.00 Very Low Very Low Very Low
Hyperalgesia 5 5.00 Very Low Very Low Very Low
Arthritis 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Binding of brain-derived neurotrophic factor (BDNF) to its specific TrkB receptor is also important for spinal activation of the ERK pathway [85, 100] (Fig. 3).
brain-derived neurotrophic factor Binding (Binding) of BDNF in spinal Positive_regulation (important) of Positive_regulation (activation) of ERK in spinal
1) Confidence 0.29 Published 2007 Journal Current Neuropharmacology Section Body Doc Link PMC2644492 Disease Relevance 0.21 Pain Relevance 0.57

General Comments

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