INT261497

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Context Info
Confidence 0.00
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.51
Pain Relevance 0.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (LMOD1) cytoskeleton (LMOD1) plasma membrane (PTGDR)
cytoplasm (LMOD1) signal transducer activity (PTGDR)
Anatomy Link Frequency
striatum 1
PTGDR (Homo sapiens)
LMOD1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Dopamine 83 99.08 Very High Very High Very High
Cannabinoid 30 84.16 Quite High
cannabis 2 80.52 Quite High
Endocannabinoid 14 50.00 Quite Low
midbrain 7 50.00 Quite Low
GABAergic 10 21.64 Low Low
Nucleus accumbens 6 14.08 Low Low
Glutamate 12 10.00 Low Low
Ventral tegmentum 16 5.00 Very Low Very Low Very Low
addiction 15 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Schizophrenia 6 83.28 Quite High
Disease 31 73.88 Quite High
Psychosis 4 72.04 Quite High
Motor Neuron Diseases 1 16.16 Low Low
Stroke 3 14.16 Low Low
Death 4 10.16 Low Low
Drug Dependence 11 5.00 Very Low Very Low Very Low
Depression 6 5.00 Very Low Very Low Very Low
Injury 6 5.00 Very Low Very Low Very Low
Stress 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In fact, the DA system undergoes extensive maturation and rearrangement until early adulthood: for example, DA innervation of terminal areas, such as the prefrontal cortex is not completed until late adolescence in the rat [168]; a reduced basal levels of DA and a reduced pool of readily releasable DA have been reported in adolescent rats [192]; D1 and D2 receptor binding in the striatum undergoes robust changes during adolescence as a consequence of extensive pruning of DA synapses [199].
D2 receptor Binding (binding) of D1 in striatum associated with dopamine
1) Confidence 0.00 Published 2007 Journal Current Neuropharmacology Section Body Doc Link PMC2644494 Disease Relevance 0.51 Pain Relevance 0.54

General Comments

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