INT261520

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Context Info
Confidence 0.06
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (DLG4, HTR2A) aging (HTR2A) protein complex assembly (DLG4)
response to stress (HTR2A) cytoplasm (HTR2A) signal transducer activity (HTR2A)
DLG4 (Homo sapiens)
HTR2A (Homo sapiens)
Pain Link Frequency Relevance Heat
Serotonin 10 99.04 Very High Very High Very High
agonist 37 98.04 Very High Very High Very High
antagonist 15 5.00 Very Low Very Low Very Low
spastic colon 12 5.00 Very Low Very Low Very Low
Migraine 7 5.00 Very Low Very Low Very Low
antidepressant 3 5.00 Very Low Very Low Very Low
Potency 3 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
abdominal pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

9 5.00 Very Low Very Low Very Low
Migraine Disorders 6 5.00 Very Low Very Low Very Low
Functional Bowel Disorder 5 5.00 Very Low Very Low Very Low
Appetite Loss 4 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Anxiety Disorder 3 5.00 Very Low Very Low Very Low
Gastroesophageal Reflux Disease 3 5.00 Very Low Very Low Very Low
Constipation 3 5.00 Very Low Very Low Very Low
Cluster Headache 2 5.00 Very Low Very Low Very Low
Abdominal Pain 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The 5–HT2A receptor contains a PDZ ligand at its extreme C terminus and directly binds to PSD-95 which augments signal transduction and inhibits agonist-induced receptor internalisation [75].
PSD-95 Binding (binds) of HT2A receptor associated with agonist
1) Confidence 0.06 Published 2007 Journal Current Neuropharmacology Section Body Doc Link PMC2644495 Disease Relevance 0 Pain Relevance 0.14

General Comments

This test has worked.

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