INT26153

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Context Info
Confidence 0.80
First Reported 1989
Last Reported 1997
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 0.10
Pain Relevance 1.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Sigmar1) nuclear envelope (Sigmar1) lipid particle (Sigmar1)
endoplasmic reticulum (Sigmar1) plasma membrane (Sigmar1) nucleus (Sigmar1)
Anatomy Link Frequency
spinal cord 1
brain 1
spleen 1
Sigmar1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 7 100.00 Very High Very High Very High
Neuropeptide 2 99.86 Very High Very High Very High
fortral 8 99.74 Very High Very High Very High
Spinal cord 6 99.52 Very High Very High Very High
opiate 1 92.96 High High
Substantia nigra 1 87.48 High High
Nucleus accumbens 1 86.76 High High
tetrodotoxin 1 75.08 Quite High
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 1 97.40 Very High Very High Very High
Psychosis 1 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Differential localization of three distinct binding sites for sigma receptor ligands in rat spleen.
Localization (localization) of sigma receptor in spleen associated with fortral
1) Confidence 0.80 Published 1997 Journal J. Neuroimmunol. Section Title Doc Link 9003244 Disease Relevance 0 Pain Relevance 0.19
The comparative localization of the sigma1 and sigma2 receptor binding sites probably relates to the differential effects of sigma1 and sigma2 drugs in the rat brain.
Localization (localization) of sigma2 receptor in brain
2) Confidence 0.55 Published 1997 Journal Neuroscience Section Abstract Doc Link 9015331 Disease Relevance 0 Pain Relevance 0.35
Neuropeptide Y and sigma receptor agonists act through a common pathway to stimulate duodenal alkaline secretion in rats.
Localization (secretion) of sigma receptor associated with agonist and neuropeptide
3) Confidence 0.28 Published 1993 Journal Eur. J. Pharmacol. Section Title Doc Link 8449231 Disease Relevance 0 Pain Relevance 0.35
The results of the present study show that PCP and sigma receptor binding sites are differentially localized in the rat spinal cord and suggest that separate binding sites exist for PCP and sigma agonists.
Localization (localized) of sigma receptor in spinal cord associated with agonist and spinal cord
4) Confidence 0.27 Published 1989 Journal Synapse Section Abstract Doc Link 2549651 Disease Relevance 0.10 Pain Relevance 0.36

General Comments

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