INT261629

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Context Info
Confidence 0.04
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.52
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (CPD) plasma membrane (TRPC5) nucleus (CPD)
transmembrane transport (TRPC5)
CPD (Homo sapiens)
TRPC5 (Homo sapiens)
Pain Link Frequency Relevance Heat
Nicotine 17 95.60 Very High Very High Very High
addiction 14 95.24 Very High Very High Very High
potassium channel 1 94.84 High High
Dopamine 1 68.00 Quite High
monoamine 3 65.08 Quite High
Catecholamine 1 58.76 Quite High
alcohol 3 11.20 Low Low
withdrawal 1 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
Opioid 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nicotine Addiction 133 95.60 Very High Very High Very High
Parkinson's Disease 1 74.88 Quite High
Alcohol Addiction 1 73.68 Quite High
Lung Cancer 4 5.00 Very Low Very Low Very Low
Cancer 4 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Reprotox - General 1 1 5.00 Very Low Very Low Very Low
Syndrome 1 5.00 Very Low Very Low Very Low
Breast Cancer 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The association of rs7050529 (IVS3+286 of TRPC5) with CPD (Table 2) is notable as a closely related family member, TRPC7, was previously significantly associated with nicotine dependence [59].
CPD Binding (association) of TRPC5 associated with addiction and nicotine
1) Confidence 0.04 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2644817 Disease Relevance 0.52 Pain Relevance 0.32

General Comments

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