INT261639

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Context Info
Confidence 0.38
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.68
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CHRNA3) plasma membrane (CHRNA3)
CHRNA3 (Homo sapiens)
Pain Link Frequency Relevance Heat
addiction 14 72.24 Quite High
Nicotine 17 71.80 Quite High
alcohol 3 5.00 Very Low Very Low Very Low
monoamine 3 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
potassium channel 1 5.00 Very Low Very Low Very Low
Dopamine 1 5.00 Very Low Very Low Very Low
Opioid 1 5.00 Very Low Very Low Very Low
Catecholamine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nicotine Addiction 133 99.46 Very High Very High Very High
Lung Cancer 4 5.00 Very Low Very Low Very Low
Cancer 4 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Reprotox - General 1 1 5.00 Very Low Very Low Very Low
Parkinson's Disease 1 5.00 Very Low Very Low Very Low
Syndrome 1 5.00 Very Low Very Low Very Low
Breast Cancer 1 5.00 Very Low Very Low Very Low
Alcohol Addiction 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Figure 3 and Table S3 summarize the associations between genotyped and imputed SNPs and CPD in PLCO and NHS smokers for the chr15q25.1 region spanning CHRNA3 and CHRNA5.
Positive_regulation (spanning) of CHRNA3 associated with nicotine addiction
1) Confidence 0.38 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2644817 Disease Relevance 0.68 Pain Relevance 0.14

General Comments

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