INT26173

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Context Info
Confidence 0.52
First Reported 1989
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 3.40
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (SELS) plasma membrane (SELS) enzyme binding (SELS)
cytoplasm (SELS)
Anatomy Link Frequency
adipose tissue 1
brachial plexus 1
SELS (Homo sapiens)
Pain Link Frequency Relevance Heat
carpal tunnel syndrome 1 97.66 Very High Very High Very High
cytokine 8 80.96 Quite High
Inflammation 12 77.28 Quite High
Peripheral nervous system 1 75.00 Quite High
rheumatoid arthritis 2 74.56 Quite High
Inflammatory marker 6 69.72 Quite High
Pain 1 10.00 Low Low
Angina 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 42 99.84 Very High Very High Very High
Disease 2 99.12 Very High Very High Very High
Injury 3 98.28 Very High Very High Very High
Obesity 142 97.92 Very High Very High Very High
Carpal Tunnel Syndrome 1 97.66 Very High Very High Very High
Nerve Root Compression 2 96.92 Very High Very High Very High
Neuropathy 2 96.52 Very High Very High Very High
Peripheral Neuropathy 1 96.10 Very High Very High Very High
Disorder Of Lipid Metabolism 24 96.04 Very High Very High Very High
Metabolic Syndrome 2 79.76 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SIGNIFICANCE: Response inhibition significantly modulates both LEPs and SEPs.
Regulation (modulates) of SEPs
1) Confidence 0.52 Published 2007 Journal Clin Neurophysiol Section Body Doc Link 17475550 Disease Relevance 0.05 Pain Relevance 0
Previous studies have suggested that the SELS gene is dysregulated in diabetes, and the data presented here indicate that the C3705T and/or the A5227G polymorphisms may play a role in this context.
Regulation (dysregulated) of SELS associated with diabetes mellitus
2) Confidence 0.27 Published 2011 Journal Metabolism Section Body Doc Link PMC3004038 Disease Relevance 1.01 Pain Relevance 0.19
Previous studies suggest a difference in SELS gene regulation depending on type 2 diabetes mellitus status in both subcutaneous [5] and omental adipose tissue [7].
Regulation (regulation) of SELS in adipose tissue associated with diabetes mellitus and obesity
3) Confidence 0.27 Published 2011 Journal Metabolism Section Body Doc Link PMC3004038 Disease Relevance 1.39 Pain Relevance 0
A study of 100 patients with peripheral nerve diseases: 30 polyneuropathies, 50 radiculopathies, 9 cases with carpal tunnel syndrome, 5 with brachial plexus injury, 6 with compressive or traumatic diseases of the peripheral nerves, demonstrates the value of the SEPs in the assessment of the nervous lesion site (central or peripheral).
Regulation (value) of SEPs in brachial plexus associated with nerve root compression, neuropathy, injury, carpal tunnel syndrome, peripheral neuropathy and disease
4) Confidence 0.02 Published 1989 Journal Neurol Psychiatr (Bucur) Section Abstract Doc Link 2551030 Disease Relevance 0.95 Pain Relevance 0.14

General Comments

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