INT261779

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.10
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Clcf1)
Anatomy Link Frequency
hippocampus 1
Clcf1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Hippocampus 22 98.44 Very High Very High Very High
Peripheral nervous system 2 89.72 High High
gABA 72 77.84 Quite High
Calcium channel 8 51.04 Quite High
Pyramidal cell 2 37.44 Quite Low
Substantia nigra 6 17.84 Low Low
GABAergic 10 6.76 Low Low
bDMF 20 5.00 Very Low Very Low Very Low
agonist 12 5.00 Very Low Very Low Very Low
anticonvulsant 10 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Acidosis 2 99.76 Very High Very High Very High
Convulsion 60 50.00 Quite Low
Stress 4 31.40 Quite Low
Epilepsy 44 5.00 Very Low Very Low Very Low
Status Epilepticus 6 5.00 Very Low Very Low Very Low
Hypoxia 4 5.00 Very Low Very Low Very Low
Injury 4 5.00 Very Low Very Low Very Low
Neurological Disease 2 5.00 Very Low Very Low Very Low
Hepatic Encephalopathy 2 5.00 Very Low Very Low Very Low
Syndrome 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Low expression of functional Clc2 has been reported in the rat neonatal hippocampus and has been correlated with the depolarizing actions of GABAA receptors at this age [205].
Gene_expression (expression) of Clc2 in hippocampus associated with hippocampus
1) Confidence 0.01 Published 2008 Journal Current Neuropharmacology Section Body Doc Link PMC2645547 Disease Relevance 0.10 Pain Relevance 0.09
In contrast, decrease in intracellular chloride occurs when potassium chloride cotransporters (KCCs), sodium dependent anion exchangers (NDAE) or chloride channel 2 (Clc2) are overexpressed.
Gene_expression (overexpressed) of Clc2
2) Confidence 0.01 Published 2008 Journal Current Neuropharmacology Section Body Doc Link PMC2645547 Disease Relevance 0 Pain Relevance 0.06

General Comments

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