INT261781

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Context Info
Confidence 0.20
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.08
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Slc12a5) intracellular (Slc12a5) transmembrane transport (Slc12a5)
Anatomy Link Frequency
neurons 2
Slc12a5 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
bDMF 10 70.08 Quite High
Limbic system 1 42.44 Quite Low
Neuronal excitability 1 37.68 Quite Low
gABA 36 5.00 Very Low Very Low Very Low
Hippocampus 11 5.00 Very Low Very Low Very Low
agonist 6 5.00 Very Low Very Low Very Low
anticonvulsant 5 5.00 Very Low Very Low Very Low
GABAergic 5 5.00 Very Low Very Low Very Low
Calcium channel 4 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 2 83.28 Quite High
Convulsion 30 50.00 Quite Low
Epilepsy 22 5.00 Very Low Very Low Very Low
Status Epilepticus 3 5.00 Very Low Very Low Very Low
Hypoxia 2 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low
Neurological Disease 1 5.00 Very Low Very Low Very Low
Hepatic Encephalopathy 1 5.00 Very Low Very Low Very Low
Syndrome 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Activation of protein kinase A pathway (PKA) pathway, through its effects on protein phosphatases, has been implicated in the activation of KCC2 following high frequency stimulation of PN2-3 rat neurons at the deep cerebellar nuclei [234].
Regulation (implicated) of Positive_regulation (activation) of KCC2 in neurons
1) Confidence 0.20 Published 2008 Journal Current Neuropharmacology Section Body Doc Link PMC2645547 Disease Relevance 0.08 Pain Relevance 0.09

General Comments

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