INT261783

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Context Info
Confidence 0.09
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.87

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Bdnf) plasma membrane (Slc12a5) intracellular (Slc12a5)
cytoplasmic membrane-bounded vesicle (Bdnf) transmembrane transport (Slc12a5)
Anatomy Link Frequency
developmental stage 4
Bdnf (Rattus norvegicus)
Slc12a5 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
bDMF 20 100.00 Very High Very High Very High
Limbic system 2 98.00 Very High Very High Very High
Neuronal excitability 2 93.24 High High
Hippocampus 22 46.16 Quite Low
Glutamate receptor 4 41.92 Quite Low
tetrodotoxin 6 40.96 Quite Low
sodium channel 2 38.88 Quite Low
gABA 72 29.76 Quite Low
Calcium channel 8 16.60 Low Low
agonist 12 12.64 Low Low
Disease Link Frequency Relevance Heat
Convulsion 60 50.00 Quite Low
Stress 4 27.44 Quite Low
Epilepsy 44 5.00 Very Low Very Low Very Low
Status Epilepticus 6 5.00 Very Low Very Low Very Low
Hypoxia 4 5.00 Very Low Very Low Very Low
Injury 4 5.00 Very Low Very Low Very Low
Neurological Disease 2 5.00 Very Low Very Low Very Low
Hepatic Encephalopathy 2 5.00 Very Low Very Low Very Low
Syndrome 2 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
BDNF exerts opposite effects on KCC2 expression, depending on the developmental stage of the target neuron.
BDNF Regulation (depending) of Gene_expression (expression) of KCC2 in developmental stage associated with bdmf
1) Confidence 0.09 Published 2008 Journal Current Neuropharmacology Section Body Doc Link PMC2645547 Disease Relevance 0 Pain Relevance 0.43
BDNF exerts opposite effects on KCC2 expression, depending on the developmental stage of the target neuron.
BDNF Regulation (effects) of Gene_expression (expression) of KCC2 in developmental stage associated with bdmf
2) Confidence 0.09 Published 2008 Journal Current Neuropharmacology Section Body Doc Link PMC2645547 Disease Relevance 0 Pain Relevance 0.43

General Comments

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