INT261789

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Context Info
Confidence 0.07
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.15
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (PDGFA) extracellular region (PDGFA) plasma membrane (Slc12a5)
intracellular (Slc12a5) embryo development (PDGFA) transmembrane transport (Slc12a5)
Anatomy Link Frequency
Platelet 2
PDGFA (Homo sapiens)
Slc12a5 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
bDMF 20 64.80 Quite High
Limbic system 2 37.16 Quite Low
Neuronal excitability 2 32.40 Quite Low
Hippocampus 22 5.68 Low Low
gABA 72 5.00 Very Low Very Low Very Low
agonist 12 5.00 Very Low Very Low Very Low
anticonvulsant 10 5.00 Very Low Very Low Very Low
GABAergic 10 5.00 Very Low Very Low Very Low
Calcium channel 8 5.00 Very Low Very Low Very Low
antagonist 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 4 78.00 Quite High
Convulsion 60 50.00 Quite Low
Epilepsy 44 5.00 Very Low Very Low Very Low
Status Epilepticus 6 5.00 Very Low Very Low Very Low
Hypoxia 4 5.00 Very Low Very Low Very Low
Injury 4 5.00 Very Low Very Low Very Low
Neurological Disease 2 5.00 Very Low Very Low Very Low
Hepatic Encephalopathy 2 5.00 Very Low Very Low Very Low
Syndrome 2 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Platelet-derived growth factor (PDGF) activates KCC2 via the PI 3-K / PP-1 pathway (phosphoinositide 3-kinase / protein phosphatase-1) [346].
PDGF Positive_regulation (activates) of KCC2 in Platelet
1) Confidence 0.07 Published 2008 Journal Current Neuropharmacology Section Body Doc Link PMC2645547 Disease Relevance 0.08 Pain Relevance 0.06
Platelet-derived growth factor (PDGF) activates KCC2 via the PI 3-K / PP-1 pathway (phosphoinositide 3-kinase / protein phosphatase-1) [346].
Platelet-derived growth factor Positive_regulation (activates) of KCC2 in Platelet
2) Confidence 0.07 Published 2008 Journal Current Neuropharmacology Section Body Doc Link PMC2645547 Disease Relevance 0.08 Pain Relevance 0.06

General Comments

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