INT261790

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.06
Pain Relevance 0.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (SHC1, Slc12a5) mitochondrion (SHC1) aging (SHC1)
intracellular (Slc12a5) transmembrane transport (Slc12a5) cytoplasm (SHC1)
SHC1 (Homo sapiens)
Slc12a5 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
bDMF 10 96.00 Very High Very High Very High
Limbic system 1 80.68 Quite High
Neuronal excitability 1 75.92 Quite High
Hippocampus 11 28.84 Quite Low
Glutamate receptor 2 24.60 Low Low
tetrodotoxin 3 23.64 Low Low
sodium channel 1 21.56 Low Low
gABA 36 12.44 Low Low
agonist 6 5.00 Very Low Very Low Very Low
anticonvulsant 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 2 59.84 Quite High
Convulsion 30 50.00 Quite Low
Epilepsy 22 5.00 Very Low Very Low Very Low
Status Epilepticus 3 5.00 Very Low Very Low Very Low
Hypoxia 2 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low
Neurological Disease 1 5.00 Very Low Very Low Very Low
Hepatic Encephalopathy 1 5.00 Very Low Very Low Very Low
Syndrome 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
signaling downregulates whereas Shc signaling upregulates KCC2 in their system [263].
Shc Positive_regulation (upregulates) of KCC2
1) Confidence 0.02 Published 2008 Journal Current Neuropharmacology Section Body Doc Link PMC2645547 Disease Relevance 0.06 Pain Relevance 0.41

General Comments

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