INT261850

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Context Info
Confidence 0.10
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.49
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transmembrane transport (Slc17a7)
Slc17a7 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Glutamate 22 100.00 Very High Very High Very High
antagonist 19 98.20 Very High Very High Very High
antidepressant 9 97.84 Very High Very High Very High
depression 3 84.80 Quite High
Serotonin 3 81.52 Quite High
noradrenaline 1 75.84 Quite High
fluoxetine 1 70.52 Quite High
Dopamine 10 53.52 Quite High
tolerance 17 48.60 Quite Low
nMDA receptor 57 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Depression 3 84.80 Quite High
Serotonin Syndrome 1 81.88 Quite High
Fever 1 74.48 Quite High
Disease 43 72.24 Quite High
Catalepsy 2 64.88 Quite High
Parkinson's Disease 6 59.36 Quite High
Ataxia 7 50.68 Quite High
Parkinsonian Disorders 2 21.20 Low Low
Muscle Rigidity 2 12.64 Low Low
Anxiety Disorder 9 9.48 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, memantine (10 mg/kg i.p.) had no effect on the CNS expression pattern of the vesicular glutamate transporter VGLUT1, upregulation of which has been proposed to be a useful marker for antidepressant activity [178].
Neg (no) Regulation (effect) of Positive_regulation (upregulation) of VGLUT1 associated with antidepressant and glutamate
1) Confidence 0.10 Published 2008 Journal Current Neuropharmacology Section Body Doc Link PMC2645549 Disease Relevance 0.49 Pain Relevance 0.58

General Comments

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