INT26187

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Context Info
Confidence 0.60
First Reported 1989
Last Reported 2004
Negated 0
Speculated 1
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 0.87
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CYCS) transport (CYCS) mitochondrion (CYCS)
small molecule metabolic process (CYCS) nucleus (CYCS)
Anatomy Link Frequency
PGE1 1
respiratory 1
CYCS (Homo sapiens)
Pain Link Frequency Relevance Heat
Opioid 3 99.98 Very High Very High Very High
lidocaine 2 97.84 Very High Very High Very High
Delta opioid receptors 2 89.68 High High
Morphine 3 87.60 High High
addiction 2 43.76 Quite Low
narcan 2 25.00 Low Low
withdrawal 1 25.00 Low Low
opiate 1 25.00 Low Low
opioid receptor 1 25.00 Low Low
antagonist 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Apoptosis 4 99.56 Very High Very High Very High
Neuroblastoma 2 97.76 Very High Very High Very High
Glioma 2 97.12 Very High Very High Very High
Reperfusion Injury 1 95.04 Very High Very High Very High
Injury 1 82.16 Quite High
Opiate Addiction 2 44.32 Quite Low
Vibrio Infection 1 27.12 Quite Low
Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The mitochondrial apoptosis-induced channel (MAC) forms in the outer membrane of mitochondria early in apoptosis and this activity is altered by physiological levels of cytochrome c.
Regulation (altered) of cytochrome c associated with apoptosis
1) Confidence 0.60 Published 2004 Journal FEBS Lett. Section Abstract Doc Link 15196916 Disease Relevance 0.34 Pain Relevance 0.10
Synergistic deleterious effect of micromolar Ca ions and free radicals on respiratory function of heart mitochondria at cytochrome C and its salvage trial.
Regulation (effect) of cytochrome C in respiratory
2) Confidence 0.44 Published 1989 Journal Biochem. Biophys. Res. Commun. Section Title Doc Link 2551286 Disease Relevance 0.18 Pain Relevance 0.07
The present article investigates chronic opioid regulation of the stimulatory adenylate cyclase-coupled prostaglandin E1 (PGE1) receptor system in neuroblastoma x glioma (NG108-15) hybrid cells.
Spec (investigates) Regulation (regulation) of cyc in PGE1 associated with neuroblastoma, opioid and glioma
3) Confidence 0.26 Published 1995 Journal J. Neurochem. Section Abstract Doc Link 7760024 Disease Relevance 0.34 Pain Relevance 0.27

General Comments

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