INT261883

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.67
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (PKD2, Ca2) lyase activity (Ca2) endoplasmic reticulum (PKD2)
cilium (PKD2) response to stress (Ca2) transmembrane transport (PKD2)
PKD2 (Homo sapiens)
Ca2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
qutenza 48 5.00 Very Low Very Low Very Low
TRP channel 18 5.00 Very Low Very Low Very Low
Pain 15 5.00 Very Low Very Low Very Low
agonist 15 5.00 Very Low Very Low Very Low
Inflammation 10 5.00 Very Low Very Low Very Low
Spinal cord 6 5.00 Very Low Very Low Very Low
cannabis 6 5.00 Very Low Very Low Very Low
Analgesic 5 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
Cannabinoid receptor 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fever 1 87.28 High High
Pressure And Volume Under Development 5 86.72 High High
Carbuncle 1 85.92 High High
Autosomal Dominant Polycystic Kidney 2 79.92 Quite High
Disease 6 76.96 Quite High
Hyperplasia 1 74.72 Quite High
Cyst 1 71.68 Quite High
Renal Failure 1 50.04 Quite High
Polycystic Kidney Disease 3 20.28 Low Low
Pain 17 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A recent report shows that triptolide, the active diterpene in the traditional Chinese medicine Lei Gong Ten, binds to TRPP2 directly and induces Ca2+ release by a TRPP2-dependent mechanism.
TRPP2 Positive_regulation (induces) of Localization (release) of Ca2
1) Confidence 0.02 Published 2008 Journal Current Neuropharmacology Section Body Doc Link PMC2645550 Disease Relevance 0.67 Pain Relevance 0

General Comments

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