INT261900

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Context Info
Confidence 0.65
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.56
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

RNA binding (Ssb) nucleus (Ssb)
Ssb (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 19 48.00 Quite Low
Analgesic 2 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
positron emission tomography 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Malignant Neoplastic Disease 25 99.84 Very High Very High Very High
Apoptosis 66 98.44 Very High Very High Very High
Death 39 97.56 Very High Very High Very High
Cancer 309 96.16 Very High Very High Very High
Prostate Cancer 4 93.16 High High
Lung Cancer 28 70.60 Quite High
Lymphatic System Cancer 26 69.20 Quite High
Necrosis 5 61.60 Quite High
Carcinoma 19 60.48 Quite High
Toxicity 7 48.52 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We have previously shown that APOMABĀ® representing the DAB4 clone of a La/SSB-specific murine monoclonal autoantibody is a malignant cell-death ligand, which accumulates preferentially in tumors in an antigen-specific and dose-dependent manner after DNA-damaging chemotherapy.
Gene_expression (representing) of SSB associated with malignant neoplastic disease, cancer and death
1) Confidence 0.65 Published 2009 Journal PLoS ONE Section Abstract Doc Link PMC2645692 Disease Relevance 1.24 Pain Relevance 0
In contradistinction to other nuclear antigens, we discovered that the abundant La ribonucleoprotein (RNP) is overexpressed in malignancy and actively induced in apoptotic malignant cells in response to DNA-damaging treatment [14].
Gene_expression (overexpressed) of La ribonucleoprotein associated with malignant neoplastic disease and apoptosis
2) Confidence 0.06 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2645682 Disease Relevance 1.31 Pain Relevance 0

General Comments

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