INT262130

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.33
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.37
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Cyp24a1) oxidoreductase activity (Cyp24a1)
Anatomy Link Frequency
intestine 3
liver 1
Cyp24a1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 34 96.32 Very High Very High Very High
Inflammatory stimuli 2 68.96 Quite High
agonist 18 60.64 Quite High
anticonvulsant 2 53.60 Quite High
Bile 78 5.00 Very Low Very Low Very Low
antagonist 14 5.00 Very Low Very Low Very Low
Crohn's disease 12 5.00 Very Low Very Low Very Low
antidepressant 6 5.00 Very Low Very Low Very Low
dexamethasone 4 5.00 Very Low Very Low Very Low
Taxol 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rickets 16 98.32 Very High Very High Very High
Inflammatory Bowel Disease 64 96.32 Very High Very High Very High
INFLAMMATION 24 90.32 High High
Infection 4 88.96 High High
Targeted Disruption 34 58.60 Quite High
Cancer 36 5.00 Very Low Very Low Very Low
Disease 20 5.00 Very Low Very Low Very Low
Breast Cancer 16 5.00 Very Low Very Low Very Low
Osteoporosis 14 5.00 Very Low Very Low Very Low
Osteogenic Sarcomas 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It upregulates CYP3A4 expression, while repressing CYP24 and CYP2D25 expression in the liver and intestine.


Negative_regulation (repressing) of Gene_expression (expression) of CYP24 in intestine
1) Confidence 0.33 Published 2009 Journal Nuclear Receptor Signaling Section Body Doc Link PMC2646121 Disease Relevance 0.68 Pain Relevance 0.18
It upregulates CYP3A4 expression, while repressing CYP24 and CYP2D25 expression in the liver and intestine.


Negative_regulation (repressing) of in liver Gene_expression (expression) of CYP24 in intestine
2) Confidence 0.11 Published 2009 Journal Nuclear Receptor Signaling Section Body Doc Link PMC2646121 Disease Relevance 0.68 Pain Relevance 0.18

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox