INT262147

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Context Info
Confidence 0.00
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.07
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (Cyp2j8) nucleus (Nr1i2) molecular_function (Cyp2j8)
DNA binding (Nr1i2) cellular_component (Cyp2j8) biological_process (Cyp2j8)
Nr1i2 (Mus musculus)
Cyp2j8 (Mus musculus)
Pain Link Frequency Relevance Heat
Taxol 2 77.52 Quite High
antidepressant 3 71.52 Quite High
Bile 39 5.00 Very Low Very Low Very Low
Inflammation 17 5.00 Very Low Very Low Very Low
agonist 9 5.00 Very Low Very Low Very Low
antagonist 7 5.00 Very Low Very Low Very Low
Crohn's disease 6 5.00 Very Low Very Low Very Low
dexamethasone 2 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
carbamazepine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Acquired Immune Deficiency Syndrome Or Hiv Infection 3 67.28 Quite High
Targeted Disruption 17 14.72 Low Low
Inflammatory Bowel Disease 32 5.00 Very Low Very Low Very Low
Cancer 18 5.00 Very Low Very Low Very Low
INFLAMMATION 12 5.00 Very Low Very Low Very Low
Disease 10 5.00 Very Low Very Low Very Low
Rickets 8 5.00 Very Low Very Low Very Low
Breast Cancer 8 5.00 Very Low Very Low Very Low
Osteoporosis 7 5.00 Very Low Very Low Very Low
Osteogenic Sarcomas 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, SXR not only regulates the expression of CYP enzymes such as CYP3A4, CYP2B6 and CYP2C8, but also conjugation enzymes (e.g., UDP-glucuronosyltransferase (UGT1A1) and sulfotransferase (SULT)) and ABC family transporters such as MDR1 and MRP2 [Dussault et al., 2001; Synold et al., 2001].
SXR Regulation (regulates) of Gene_expression (expression) of CYP2C8
1) Confidence 0.00 Published 2009 Journal Nuclear Receptor Signaling Section Body Doc Link PMC2646121 Disease Relevance 0.07 Pain Relevance 0.07

General Comments

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