INT262151

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Context Info
Confidence 0.24
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.24
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Vdr) mitochondrion (Cyp24a1) oxidoreductase activity (Cyp24a1)
cell morphogenesis (Vdr) nucleus (Vdr) DNA binding (Vdr)
Anatomy Link Frequency
kidney 1
Vdr (Mus musculus)
Cyp24a1 (Mus musculus)
Pain Link Frequency Relevance Heat
Bile 39 73.36 Quite High
antiepileptic Drug 1 72.72 Quite High
carbamazepine 1 67.92 Quite High
agonist 9 51.76 Quite High
Inflammation 17 5.00 Very Low Very Low Very Low
antagonist 7 5.00 Very Low Very Low Very Low
Crohn's disease 6 5.00 Very Low Very Low Very Low
antidepressant 3 5.00 Very Low Very Low Very Low
dexamethasone 2 5.00 Very Low Very Low Very Low
Taxol 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Toxicity 4 67.36 Quite High
Metabolic Bone Disease 1 62.08 Quite High
Rickets 8 60.08 Quite High
Targeted Disruption 17 55.44 Quite High
Inflammatory Bowel Disease 32 5.00 Very Low Very Low Very Low
Cancer 18 5.00 Very Low Very Low Very Low
INFLAMMATION 12 5.00 Very Low Very Low Very Low
Disease 10 5.00 Very Low Very Low Very Low
Breast Cancer 8 5.00 Very Low Very Low Very Low
Osteoporosis 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CYP24 is directly regulated by VDR and it is expressed mainly in the kidney where VDR is also abundant.
VDR Regulation (regulated) of CYP24 in kidney
1) Confidence 0.24 Published 2009 Journal Nuclear Receptor Signaling Section Body Doc Link PMC2646121 Disease Relevance 0.24 Pain Relevance 0.23

General Comments

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