INT262185

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Context Info
Confidence 0.04
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.56
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Ncoa1, Nr1i2) DNA binding (Ncoa1, Nr1i2) signal transduction (Ncoa1)
transferase activity, transferring acyl groups (Ncoa1) signal transducer activity (Ncoa1)
Ncoa1 (Mus musculus)
Nr1i2 (Mus musculus)
Pain Link Frequency Relevance Heat
antidepressant 3 85.08 High High
depression 1 73.88 Quite High
Bile 39 20.60 Low Low
Inflammation 17 5.00 Very Low Very Low Very Low
agonist 9 5.00 Very Low Very Low Very Low
antagonist 7 5.00 Very Low Very Low Very Low
Crohn's disease 6 5.00 Very Low Very Low Very Low
dexamethasone 2 5.00 Very Low Very Low Very Low
Taxol 2 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sleep Disorders 1 77.24 Quite High
Affective Disorder 1 76.40 Quite High
Anxiety Disorder 1 75.24 Quite High
Depression 1 73.88 Quite High
Diarrhoea 1 64.76 Quite High
Jaundice 1 64.36 Quite High
Dysentery 1 63.96 Quite High
Contusions 1 63.52 Quite High
Lung Cancer 1 33.64 Quite Low
Cancer 18 30.88 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It can also promote recruitment of the coactivator SRC-1 to SXR and displaces radiolabeled ligand bound to SXR, suggesting a direct interaction with the receptor.
Positive_regulation (promote) of SRC-1 Binding (recruitment) of SXR
1) Confidence 0.04 Published 2009 Journal Nuclear Receptor Signaling Section Body Doc Link PMC2646121 Disease Relevance 0.56 Pain Relevance 0.12

General Comments

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