INT262187

Context Info Confidence 0.24 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.21 Pain Relevance 0.06

endosome (Abcg1) transport (Abcg1) Golgi apparatus (Abcg1) intracellular (Abcg1) DNA binding (Nr1i2) nucleus (Nr1i2)

Nr1i2 (Mus musculus) Abcg1 (Mus musculus)

Pain Link Frequency Relevance Heat Bile 39 62.80 Inflammation 17 5.00 agonist 9 5.00 antagonist 7 5.00 Crohn's disease 6 5.00 antidepressant 3 5.00 dexamethasone 2 5.00 Taxol 2 5.00 palliative 1 5.00 carbamazepine 1 5.00

Disease Link Frequency Relevance Heat Targeted Disruption 17 74.52 Neurodegenerative Disease 1 69.52 Van Bogaert's Disease 1 68.36 Inflammatory Bowel Disease 32 5.00 Cancer 18 5.00 INFLAMMATION 12 5.00 Disease 10 5.00 Rickets 8 5.00 Breast Cancer 8 5.00 Osteoporosis 7 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Moreover, the authors showed that SXR can also induce ABCA1 and ABCG1 expression and promote cholesterol efflux in the same cells.

SXR Positive_regulation (induce) of Gene_expression (expression) of ABCG1

1) Confidence 0.24 Published 2009 Journal Nuclear Receptor Signaling Section Body Doc Link PMC2646121 Disease Relevance 0.21 Pain Relevance 0.06

General Comments

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