INT262207

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Context Info
Confidence 0.14
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.08
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Nr1i2, Ep300) DNA binding (Nr1i2, Ep300) transferase activity, transferring acyl groups (Ep300)
transcription factor binding (Ep300) cytoplasm (Ep300)
Nr1i2 (Mus musculus)
Ep300 (Mus musculus)
Pain Link Frequency Relevance Heat
Bile 78 57.36 Quite High
Inflammation 34 5.00 Very Low Very Low Very Low
agonist 18 5.00 Very Low Very Low Very Low
antagonist 14 5.00 Very Low Very Low Very Low
Crohn's disease 12 5.00 Very Low Very Low Very Low
antidepressant 6 5.00 Very Low Very Low Very Low
dexamethasone 4 5.00 Very Low Very Low Very Low
Taxol 4 5.00 Very Low Very Low Very Low
palliative 2 5.00 Very Low Very Low Very Low
carbamazepine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 34 96.80 Very High Very High Very High
Osteoporosis 14 93.36 High High
Osteogenic Sarcomas 10 43.48 Quite Low
Liver Disease 2 23.04 Low Low
Colon Cancer 4 21.60 Low Low
Inflammatory Bowel Disease 64 5.00 Very Low Very Low Very Low
Cancer 36 5.00 Very Low Very Low Very Low
INFLAMMATION 24 5.00 Very Low Very Low Very Low
Disease 20 5.00 Very Low Very Low Very Low
Rickets 16 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Upon activation by vitamin K2, SXR can be recruited together with a coactivator, p300, to the SXR response element in the Msx2 promoter.
SXR Binding (recruited) of p300
1) Confidence 0.14 Published 2009 Journal Nuclear Receptor Signaling Section Body Doc Link PMC2646121 Disease Relevance 0.54 Pain Relevance 0.06
Upon activation by vitamin K2, SXR can be recruited together with a coactivator, p300, to the SXR response element in the Msx2 promoter.
SXR Binding (recruited) of p300
2) Confidence 0.13 Published 2009 Journal Nuclear Receptor Signaling Section Body Doc Link PMC2646121 Disease Relevance 0.54 Pain Relevance 0.06

General Comments

This test has worked.

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