INT262255

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Context Info
Confidence 0.05
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 3.00
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (APC, F2R) Golgi apparatus (F2R) protein complex assembly (APC)
signal transducer activity (F2R) cytoplasm (APC) cytosol (APC)
APC (Homo sapiens)
F2R (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 10 96.68 Very High Very High Very High
cytokine 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 8 96.68 Very High Very High Very High
Apoptosis 2 95.80 Very High Very High Very High
Pressure And Volume Under Development 12 90.40 High High
Sepsis 14 84.64 Quite High
Lung Injury 32 84.28 Quite High
Adult Respiratory Distress Syndrome 56 81.24 Quite High
Respiratory Failure 2 77.92 Quite High
Pneumonia 4 73.20 Quite High
Stroke 10 5.00 Very Low Very Low Very Low
Cv General 4 Under Development 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It has been suggested that, by binding to endothelial APC receptor (EPCR) and to protease activated receptor-1 (PAR-1), APC initiates cytoprotective reactions, gene expression profile alterations, and anti-inflammatory and anti-apoptotic effects [8-11].
APC Binding (binding) of PAR-1 associated with inflammation and apoptosis
1) Confidence 0.05 Published 2008 Journal Crit Care Section Body Doc Link PMC2646309 Disease Relevance 1.50 Pain Relevance 0.05
It has been suggested that, by binding to endothelial APC receptor (EPCR) and to protease activated receptor-1 (PAR-1), APC initiates cytoprotective reactions, gene expression profile alterations, and anti-inflammatory and anti-apoptotic effects [8-11].
APC Binding (binding) of protease activated receptor-1 associated with inflammation and apoptosis
2) Confidence 0.05 Published 2008 Journal Crit Care Section Body Doc Link PMC2646309 Disease Relevance 1.50 Pain Relevance 0.05

General Comments

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