INT262262

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.34
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (LRSAM1) ligase activity (LRSAM1) cytoplasm (LRSAM1)
Anatomy Link Frequency
kidney 1
LRSAM1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 5 10.08 Low Low
cINOD 4 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Renal Disease 8 100.00 Very High Very High Very High
Sepsis 16 99.16 Very High Very High Very High
Injury 50 99.12 Very High Very High Very High
Renal Failure 15 91.96 High High
Hyperglycemia 3 82.00 Quite High
Diabetes Mellitus 41 64.60 Quite High
INFLAMMATION 7 10.08 Low Low
Hypoglycemia 10 5.00 Very Low Very Low Very Low
Chronic Renal Failure 10 5.00 Very Low Very Low Very Low
Acute Renal Failure 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We also noted the evolution of urine output, the risk of renal dysfunction, injury to the kidney, failure of kidney function, loss of kidney function and end-stage kidney disease (RIFLE) classification and sepsis related organ failure assessment (SOFA) score over 3 weeks.


Negative_regulation (loss) of RIFLE in kidney associated with injury, renal disease and sepsis
1) Confidence 0.03 Published 2010 Journal Crit Care Section Abstract Doc Link PMC2887149 Disease Relevance 0.69 Pain Relevance 0
In the present study, tight perioperative glycemic control is associated with a significant reduction in severe RIFLE scoring.
Negative_regulation (reduction) of RIFLE
2) Confidence 0.02 Published 2008 Journal Crit Care Section Body Doc Link PMC2646319 Disease Relevance 0.64 Pain Relevance 0

General Comments

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