INT262284

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Context Info
Confidence 0.06
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.79
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transmembrane transporter activity (Slc22a6) plasma membrane (Slc22a6) protein complex (Slc22a6)
Slc22a6 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
methotrexate 2 98.48 Very High Very High Very High
cINOD 1 97.92 Very High Very High Very High
aspirin 1 96.24 Very High Very High Very High
ischemia 1 83.80 Quite High
vincristine 1 68.12 Quite High
Bile 1 32.56 Quite Low
Morphine 5 7.60 Low Low
Patient controlled alalgesia 2 5.00 Very Low Very Low Very Low
Codeine 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 92 100.00 Very High Very High Very High
INFLAMMATION 3 97.20 Very High Very High Very High
Cv Unclassified Under Development 1 83.80 Quite High
Renal Disease 6 31.12 Quite Low
Chronic Renal Failure 8 5.52 Low Low
Critical Illness 7 5.00 Very Low Very Low Very Low
Uremia 4 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Hypoxia 2 5.00 Very Low Very Low Very Low
Liver Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although the role played by OATs in nonrenal drug clearance has not been characterized, decreased OAT1 and OAT3 activity as a result of AKI could decrease the renal secretion of drugs such as methotrexate, nonsteroidal anti-inflammatory drugs, and acetylsalicylic acid [16].
Negative_regulation (decrease) of Positive_regulation (result) of OAT1 associated with aspirin, inflammation, injury, cinod and methotrexate
1) Confidence 0.06 Published 2008 Journal Crit Care Section Body Doc Link PMC2646335 Disease Relevance 0.79 Pain Relevance 0.31

General Comments

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