INT262317

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Context Info
Confidence 0.31
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 7
Total Number 7
Disease Relevance 9.67
Pain Relevance 2.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (TAF9) nucleolus (TAF9) nucleus (TAF9)
DNA binding (TAF9) kinase activity (TAF9)
Anatomy Link Frequency
nerve 1
TAF9 (Homo sapiens)
Pain Link Frequency Relevance Heat
Congenital analgesia 17 100.00 Very High Very High Very High
Visceral pain 1 99.92 Very High Very High Very High
cannabis 245 99.48 Very High Very High Very High
Pain 38 98.96 Very High Very High Very High
Inflammatory mediators 5 96.96 Very High Very High Very High
corticosteroid 120 95.92 Very High Very High Very High
cytokine 35 89.04 High High
Inflammatory response 15 88.12 High High
Paroxysmal extreme pain disorder 6 81.68 Quite High
antagonist 6 80.72 Quite High
Disease Link Frequency Relevance Heat
Muscle Disease 455 100.00 Very High Very High Very High
Neuropathy 400 100.00 Very High Very High Very High
Psychosis 61 100.00 Very High Very High Very High
Pain 55 100.00 Very High Very High Very High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super / Visceral Pain

1 99.92 Very High Very High Very High
Nervous System Injury 5 99.52 Very High Very High Very High
INFLAMMATION 43 96.56 Very High Very High Very High
Critical Illness 105 94.84 High High
Cv Unclassified Under Development 10 94.68 High High
Hypoxia 5 93.96 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The association between CIP/CIM and other organ failures has raised the question as to whether neuromuscular involvement is not simply a part of a systemic critical illness, representing just another organ failure.
CIP Binding (association) of associated with neuropathy, critical illness and muscle disease
1) Confidence 0.31 Published 2008 Journal Crit Care Section Body Doc Link PMC2646339 Disease Relevance 2.18 Pain Relevance 0.24
CIP/CIM is associated with increased hospital and intensive care unit (ICU) stays and increased mortality rates.
CIP Binding (associated) of associated with neuropathy and muscle disease
2) Confidence 0.31 Published 2008 Journal Crit Care Section Abstract Doc Link PMC2646339 Disease Relevance 1.76 Pain Relevance 0.04
CIP/CIM is associated with increased ICU and hospital stays [41,49] and elevated mortality rates [41,42,49,50], although other data suggest that patient selection may partially explain this [20].
CIP Binding (associated) of associated with neuropathy and muscle disease
3) Confidence 0.30 Published 2008 Journal Crit Care Section Body Doc Link PMC2646339 Disease Relevance 1.49 Pain Relevance 0
Functional denervation resulting from nerve injury in CIP may provide the link between CIP and CIM.
CIP Binding (link) of in nerve associated with neuropathy, nervous system injury and muscle disease
4) Confidence 0.27 Published 2008 Journal Crit Care Section Body Doc Link PMC2646339 Disease Relevance 1.34 Pain Relevance 0.43
Aminoglycosides have received particular attention as two studies associated their use with CIP [40,42].
CIP Binding (associated) of associated with neuropathy
5) Confidence 0.26 Published 2008 Journal Crit Care Section Body Doc Link PMC2646339 Disease Relevance 1.16 Pain Relevance 0.03
CIP presents immediately after birth and is characterized mainly by insensitivity to pain which is the common feature among all affected individuals, although clinical heterogeneity exists, as some patients develop anosmia while others have intact smell sensation.
CIP Binding (characterized) of associated with pain, congenital analgesia and loss of sense of smell
6) Confidence 0.20 Published 2010 Journal Dermatology (Basel, Switzerland) Section Body Doc Link PMC2969160 Disease Relevance 1.38 Pain Relevance 1.07
The question here is, since those at risk of getting CIP or SSD with cannabis are few, is it justified to incarcerate the vast majority of people who may use cannabis without any harm?.
CIP Binding (getting) of associated with cannabis and psychosis
7) Confidence 0.03 Published 2010 Journal Subst Abuse Treat Prev Policy Section Body Doc Link PMC2910013 Disease Relevance 0.26 Pain Relevance 0.34

General Comments

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