INT262514

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Context Info
Confidence 0.20
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.64
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transmembrane transporter activity (Aqp1) plasma membrane (Aqp1) nucleus (Aqp1)
cytoplasm (Aqp1)
Aqp1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Central nervous system 13 5.00 Very Low Very Low Very Low
ischemia 4 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
potassium channel 3 5.00 Very Low Very Low Very Low
nMDA receptor 3 5.00 Very Low Very Low Very Low
Glutamate receptor 3 5.00 Very Low Very Low Very Low
Dopamine 3 5.00 Very Low Very Low Very Low
midbrain 2 5.00 Very Low Very Low Very Low
Neurotransmitter 2 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 165 99.12 Very High Very High Very High
Stress 11 87.00 High High
Cancer 3 62.80 Quite High
Toxicity 2 15.68 Low Low
Death 31 5.00 Very Low Very Low Very Low
Disease 17 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 14 5.00 Very Low Very Low Very Low
Necrosis 8 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 8 5.00 Very Low Very Low Very Low
Hypoxia 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Sterically blocking AQP1 activity with HgCl2 was shown to prevent AVD and the subsequent downstream apoptotic events such as cell shrinkage, DNA degradation, loss of mitochondrial membrane permeability and caspase 3 activation [54].
AQP1 Binding (activity) of associated with apoptosis
1) Confidence 0.20 Published 2008 Journal Current Neuropharmacology Section Body Doc Link PMC2647147 Disease Relevance 0.64 Pain Relevance 0

General Comments

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