INT262548

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Context Info
Confidence 0.45
First Reported 2008
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.73
Pain Relevance 2.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Trpv1) transport (Trpv1) plasma membrane (Trpv1)
transmembrane transport (Trpv1) lipid metabolic process (Trpv1)
Anatomy Link Frequency
body 2
Trpv1 (Mus musculus)
Pain Link Frequency Relevance Heat
amygdala 126 100.00 Very High Very High Very High
long-term potentiation 75 100.00 Very High Very High Very High
calcitonin gene related peptide 14 100.00 Very High Very High Very High
substance P 11 100.00 Very High Very High Very High
isoflurane 11 94.24 High High
Pain 35 92.96 High High
qutenza 153 91.44 High High
antagonist 49 90.40 High High
Nerve growth factor 8 86.08 High High
Endocannabinoid 8 84.28 Quite High
Disease Link Frequency Relevance Heat
Nociception 18 98.52 Very High Very High Very High
Pain 43 92.96 High High
Coronary Artery Disease 2 78.00 Quite High
Cancer Pain 1 65.36 Quite High
Bone Cancer 1 65.16 Quite High
Diabetes Mellitus 6 61.52 Quite High
Peripheral Neuropathy 2 60.80 Quite High
Increased Venous Pressure Under Development 6 58.72 Quite High
Decapitation 1 34.48 Quite Low
Hemorrhage 2 22.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Of concern are the maintenance of body temperature, TRPV1-mediated SP and CGRP release and their subsequent effect on the cardiovascular functions and acute nociception.
Regulation (effect) of Localization (release) of TRPV1 in body associated with nociception, calcitonin gene related peptide and substance p
1) Confidence 0.45 Published 2008 Journal Current Neuropharmacology Section Body Doc Link PMC2647151 Disease Relevance 0.73 Pain Relevance 0.90
Sensitization of TRPV1 enhances LA-LTP
Regulation (-) of Localization (Sensitization) of TRPV1 associated with long-term potentiation and amygdala
2) Confidence 0.44 Published 2011 Journal PLoS ONE Section Body Doc Link PMC3020947 Disease Relevance 0 Pain Relevance 1.35

General Comments

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