INT262551

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.43
Pain Relevance 0.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Vipr1) plasma membrane (Vipr1) nucleus (Vipr1)
cytoplasm (Vipr1) signal transducer activity (Vipr1)
Anatomy Link Frequency
sensory neurons 2
Vipr1 (Mus musculus)
Pain Link Frequency Relevance Heat
calcitonin gene related peptide 14 100.00 Very High Very High Very High
substance P 11 100.00 Very High Very High Very High
bradykinin 6 100.00 Very High Very High Very High
Neuropeptide 2 100.00 Very High Very High Very High
agonist 13 83.76 Quite High
Dopamine 4 78.56 Quite High
Inflammation 19 69.28 Quite High
Thermal hyperalgesia 2 68.24 Quite High
qutenza 74 64.60 Quite High
Inflammatory mediators 4 63.04 Quite High
Disease Link Frequency Relevance Heat
Nociception 16 98.54 Very High Very High Very High
INFLAMMATION 21 69.28 Quite High
Hyperalgesia 7 68.24 Quite High
Pain 38 5.00 Very Low Very Low Very Low
Targeted Disruption 12 5.00 Very Low Very Low Very Low
Diabetes Mellitus 6 5.00 Very Low Very Low Very Low
Overactive Bladder 6 5.00 Very Low Very Low Very Low
Neuropathic Pain 6 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 6 5.00 Very Low Very Low Very Low
Anxiety Disorder 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Activation of Ca2+ permeant nociceptive ion channels on the peripheral and central terminals of sensory neurons leads to the synthesis and/or release of a variety of proinflammatory agents and neuropeptides, like ATP, BK, PGs, CGRP, SP and vasoactive intestinal peptide (VIP) [105, 114].
Positive_regulation (leads) of Localization (release) of intestinal peptide in sensory neurons associated with nociception, calcitonin gene related peptide, neuropeptide, bradykinin and substance p
1) Confidence 0.01 Published 2008 Journal Current Neuropharmacology Section Body Doc Link PMC2647151 Disease Relevance 0.43 Pain Relevance 0.62

General Comments

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