INT262566

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Context Info
Confidence 0.20
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.57
Pain Relevance 0.71

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Trpv1) transport (Trpv1) plasma membrane (Trpv1)
transmembrane transport (Trpv1) lipid metabolic process (Trpv1)
Anatomy Link Frequency
stomach 1
Par2 (Mus musculus)
Trpv1 (Mus musculus)
Pain Link Frequency Relevance Heat
qutenza 74 93.32 High High
substance P 11 84.80 Quite High
calcitonin gene related peptide 14 84.52 Quite High
Pain 30 80.28 Quite High
cOX1 2 75.68 Quite High
Inflammation 19 72.32 Quite High
Potency 2 60.40 Quite High
c fibre 4 52.72 Quite High
burning pain 1 50.88 Quite High
interstitial cystitis 1 38.76 Quite Low
Disease Link Frequency Relevance Heat
Increased Venous Pressure Under Development 6 94.40 High High
Ganglion Cysts 2 87.92 High High
Pain 38 80.28 Quite High
INFLAMMATION 21 72.32 Quite High
Hemorrhage 2 66.16 Quite High
Abnormal Reflex 3 64.04 Quite High
Nociception 16 45.76 Quite Low
Overactive Bladder 6 44.00 Quite Low
Interstitial Cystitis 1 38.76 Quite Low
Targeted Disruption 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The protease-activated receptor 2 (PAR2), a Gq-coupled receptor is suggested to sensitize TRPV1 by PKC activation in the stomach, enhancing gastric protection by increasing gastric mucus secretion.
PAR2 Regulation (sensitize) of TRPV1 in stomach
1) Confidence 0.20 Published 2008 Journal Current Neuropharmacology Section Body Doc Link PMC2647151 Disease Relevance 0.57 Pain Relevance 0.71

General Comments

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