INT262569

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Context Info
Confidence 0.00
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.75
Pain Relevance 0.76

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Pax3, Calca) cell proliferation (Pax3) extracellular space (Calca)
extracellular region (Calca) intracellular (Calca) DNA binding (Pax3)
Anatomy Link Frequency
nerve 1
Pax3 (Mus musculus)
Calca (Mus musculus)
Pain Link Frequency Relevance Heat
calcitonin gene related peptide 14 100.00 Very High Very High Very High
substance P 11 100.00 Very High Very High Very High
agonist 13 99.20 Very High Very High Very High
qutenza 74 98.56 Very High Very High Very High
interstitial cystitis 1 80.56 Quite High
Inflammation 19 63.88 Quite High
Pain 30 59.76 Quite High
c fibre 4 58.32 Quite High
burning pain 1 55.60 Quite High
Potency 2 36.16 Quite Low
Disease Link Frequency Relevance Heat
Overactive Bladder 6 95.40 Very High Very High Very High
Interstitial Cystitis 1 80.56 Quite High
Abnormal Reflex 3 76.80 Quite High
Targeted Disruption 12 69.32 Quite High
INFLAMMATION 21 63.88 Quite High
Pain 38 59.76 Quite High
Stress Incontinence 1 38.88 Quite Low
Asthma 3 23.84 Low Low
Cough 2 21.84 Low Low
Disease 4 19.04 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Intravesical administration of capsaicin and RTX, a potent TRPV1 agonist results in a marked decrease in TRPV1, SP and CGRP immunoreactivity in the rat urinary bladder [13, 14], which may be as a result of nerve terminal degeneration mediated by these agents [27, 35, 37, 40, 146, 163].
SP Regulation (immunoreactivity) of CGRP in nerve associated with calcitonin gene related peptide, qutenza, agonist and substance p
1) Confidence 0.00 Published 2008 Journal Current Neuropharmacology Section Body Doc Link PMC2647151 Disease Relevance 0.75 Pain Relevance 0.76

General Comments

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