INT262578

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.71
Pain Relevance 0.75

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Prkaca, Calca) nucleus (Prkaca, Calca) mitochondrion (Prkaca)
Golgi apparatus (Prkaca) intracellular (Calca) protein complex (Prkaca)
Anatomy Link Frequency
neurons 2
Prkaca (Mus musculus)
Calca (Mus musculus)
Pain Link Frequency Relevance Heat
qutenza 74 100.00 Very High Very High Very High
calcitonin gene related peptide 14 100.00 Very High Very High Very High
Hyperalgesia 5 99.48 Very High Very High Very High
Inflammation 19 95.08 Very High Very High Very High
Neuropeptide 2 94.48 High High
Cannabinoid 1 91.84 High High
Inflammatory mediators 4 77.72 Quite High
Thermal hyperalgesia 2 68.36 Quite High
substance P 11 50.32 Quite High
bradykinin 6 49.72 Quite Low
Disease Link Frequency Relevance Heat
Hyperalgesia 7 99.48 Very High Very High Very High
INFLAMMATION 21 95.08 Very High Very High Very High
Nociception 16 65.00 Quite High
Pain 38 5.00 Very Low Very Low Very Low
Targeted Disruption 12 5.00 Very Low Very Low Very Low
Diabetes Mellitus 6 5.00 Very Low Very Low Very Low
Overactive Bladder 6 5.00 Very Low Very Low Very Low
Neuropathic Pain 6 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 6 5.00 Very Low Very Low Very Low
Anxiety Disorder 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PKA-mediated phosphorylation of TRPV1 potentiates capsaicin-mediated current and increase CGRP release in cultured DRG neurons [64, 70, 102].
PKA Positive_regulation (increase) of Localization (release) of CGRP in neurons associated with calcitonin gene related peptide and qutenza
1) Confidence 0.03 Published 2008 Journal Current Neuropharmacology Section Body Doc Link PMC2647151 Disease Relevance 0.71 Pain Relevance 0.75

General Comments

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