INT262586

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Context Info
Confidence 0.09
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.90
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

isomerase activity (Rpe) carbohydrate metabolic process (Rpe)
Anatomy Link Frequency
photoreceptor 2
glial cells 2
Rpe (Mus musculus)
Pain Link Frequency Relevance Heat
Glutamate 29 5.00 Very Low Very Low Very Low
ischemia 12 5.00 Very Low Very Low Very Low
nMDA receptor 9 5.00 Very Low Very Low Very Low
Glutamate receptor 6 5.00 Very Low Very Low Very Low
antagonist 5 5.00 Very Low Very Low Very Low
Neurotransmitter 5 5.00 Very Low Very Low Very Low
Central nervous system 3 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
gABA 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Increased Venous Pressure Under Development 6 99.88 Very High Very High Very High
Disease 17 99.68 Very High Very High Very High
Hyperuricemia 1 98.08 Very High Very High Very High
Hyperlipidemia 2 97.78 Very High Very High Very High
Diabetes Mellitus 13 97.02 Very High Very High Very High
Metabolic Syndrome 1 84.48 Quite High
Retinal Diseases 8 78.00 Quite High
Night Blindness 1 68.08 Quite High
Retinoschisis 1 66.72 Quite High
Respiratory Syncytial Virus 13 66.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, most studies have focused on diseases that primarily affect the photoreceptor, RPE, and RGC layer.
Regulation (affect) of RPE Binding (photoreceptor) of in photoreceptor associated with disease
1) Confidence 0.09 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2713732 Disease Relevance 1.00 Pain Relevance 0
On the other hand all other systemic metabolic problems of the organism like diabetes mellitus, hyperlipidemia, hypercholesterolemia, hyperuricemia, high systemic blood pressure and periods of very low perfusion pressure due to vasospasm also affect the microenvironment of the RGCs and RPE – from the capillaries via the extracellular space via the glial cells down to the intracellular “milieu” of these neurons.
Regulation (affect) of RPE Binding (microenvironment) of in glial cells associated with hyperuricemia, diabetes mellitus, increased venous pressure under development and hyperlipidemia
2) Confidence 0.02 Published 2008 Journal Current Neuropharmacology Section Body Doc Link PMC2647152 Disease Relevance 0.90 Pain Relevance 0

General Comments

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