INT262590

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.82
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

isomerase activity (Renbp)
Anatomy Link Frequency
neuronal 1
extracellular matrix 1
Renbp (Mus musculus)
Pain Link Frequency Relevance Heat
fibrosis 1 48.28 Quite Low
rheumatoid arthritis 1 47.04 Quite Low
Kinase C 1 26.88 Quite Low
Glutamate 29 5.00 Very Low Very Low Very Low
ischemia 12 5.00 Very Low Very Low Very Low
nMDA receptor 9 5.00 Very Low Very Low Very Low
Glutamate receptor 6 5.00 Very Low Very Low Very Low
antagonist 5 5.00 Very Low Very Low Very Low
Neurotransmitter 5 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetic Retinopathy 6 88.00 High High
Myeloid Leukemia 3 85.96 High High
Age-related Macular Degeneration 8 82.40 Quite High
Diabetes Mellitus 13 72.28 Quite High
Disease Progression 3 64.56 Quite High
Aging 4 62.40 Quite High
Stress 23 56.24 Quite High
Ocular Toxicity (including Many Sub-types) 1 54.88 Quite High
Neurodegenerative Disease 5 50.00 Quite Low
Cancer 1 49.12 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, AGE accumulation was increased within the retinal extracellular matrix and attenuation of the RAGE axis with soluble RAGE ameliorated neuronal dysfunction and reduced the development of capillary lesions in these mice [7].
Positive_regulation (increased) of in extracellular matrix Positive_regulation (accumulation) of AGE in neuronal
1) Confidence 0.01 Published 2008 Journal Current Neuropharmacology Section Body Doc Link PMC2647152 Disease Relevance 0.82 Pain Relevance 0

General Comments

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