INT262635

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Context Info
Confidence 0.05
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.53
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (HLA-DQA1, HLA-DRA) Golgi apparatus (HLA-DQA1, HLA-DRA) endoplasmic reticulum (HLA-DQA1, HLA-DRA)
plasma membrane (HLA-DQA1, HLA-DRA) lysosome (HLA-DRA)
HLA-DQA1 (Homo sapiens)
HLA-DRA (Homo sapiens)
Pain Link Frequency Relevance Heat
spinal inflammation 8 26.16 Quite Low
rheumatoid arthritis 7 24.12 Low Low
Multiple sclerosis 12 23.04 Low Low
Central nervous system 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
psoriasis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Autoimmune Disease 45 99.76 Very High Very High Very High
Diabetes Mellitus 17 99.48 Very High Very High Very High
Disease 23 43.48 Quite Low
Systemic Lupus Erythematosus 6 27.72 Quite Low
Low Back Pain 8 26.16 Quite Low
Graves' Ophthalmopathy 3 24.48 Low Low
Rheumatoid Arthritis 7 24.12 Low Low
Demyelinating Disease 12 23.04 Low Low
Disease Susceptibility 4 6.32 Low Low
Viral Infection 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Early experiments investigating association of HLA-DR and -DQ with AID in T1D indicated a strong association of the DRB1*03 and DRB1*04 alleles [8-10].
DQ Binding (association) of HLA-DR associated with autoimmune disease and diabetes mellitus
1) Confidence 0.05 Published 2007 Journal Current Genomics Section Body Doc Link PMC2647156 Disease Relevance 0.53 Pain Relevance 0

General Comments

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