INT262710

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Context Info
Confidence 0.00
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.85
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Crem, Hif1a) DNA binding (Crem, Hif1a) cell differentiation (Hif1a)
signal transduction (Hif1a) nucleolus (Hif1a) protein binding transcription factor activity (Hif1a)
Crem (Mus musculus)
Hif1a (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 22 5.00 Very Low Very Low Very Low
Central nervous system 10 5.00 Very Low Very Low Very Low
ischemia 10 5.00 Very Low Very Low Very Low
Peripheral nervous system 8 5.00 Very Low Very Low Very Low
cytokine 6 5.00 Very Low Very Low Very Low
cINOD 6 5.00 Very Low Very Low Very Low
Nav1.1 6 5.00 Very Low Very Low Very Low
sodium channel 4 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 28 100.00 Very High Very High Very High
Disease 306 98.16 Very High Very High Very High
Death 16 96.36 Very High Very High Very High
Parkinson's Disease 2 50.48 Quite High
Stress 52 44.24 Quite Low
Targeted Disruption 62 5.00 Very Low Very Low Very Low
Alzheimer's Dementia 44 5.00 Very Low Very Low Very Low
Syndrome 30 5.00 Very Low Very Low Very Low
Cognitive Disorder 26 5.00 Very Low Very Low Very Low
INFLAMMATION 26 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
During hypoxia, the hypoxia-inducible factor-1 (HIF-1) transcription factor binds to the hypoxia-responsive element (HRE) in target gene promoters and activates genes involved in energy metabolism and cell death [183].
hypoxia-responsive element Binding (binds) of hypoxia-inducible factor-1 associated with hypoxia and death
1) Confidence 0.00 Published 2007 Journal Current Genomics Section Body Doc Link PMC2647160 Disease Relevance 0.93 Pain Relevance 0
During hypoxia, the hypoxia-inducible factor-1 (HIF-1) transcription factor binds to the hypoxia-responsive element (HRE) in target gene promoters and activates genes involved in energy metabolism and cell death [183].
hypoxia-responsive element Binding (binds) of HIF-1 associated with hypoxia and death
2) Confidence 0.00 Published 2007 Journal Current Genomics Section Body Doc Link PMC2647160 Disease Relevance 0.92 Pain Relevance 0

General Comments

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