INT262751

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Context Info
Confidence 0.25
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.29
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (PTCH1, SMO) plasma membrane (PTCH1, SMO) signal transduction (PTCH1)
cilium (SMO) cytoplasm (SMO) signal transducer activity (SMO)
PTCH1 (Homo sapiens)
SMO (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 2 95.48 Very High Very High Very High
headache 8 17.84 Low Low
positron emission tomography 8 5.00 Very Low Very Low Very Low
peripheral neuropathy 4 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Bioavailability 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Glioma 2 92.88 High High
Cancer 76 79.68 Quite High
Basal Cell Neoplasms 10 77.28 Quite High
Solid Tumor 12 70.24 Quite High
Carcinoma 4 68.64 Quite High
Disease 28 62.60 Quite High
Syndrome 2 51.80 Quite High
Proteinuria 4 49.76 Quite Low
Hypertension 4 48.92 Quite Low
Lymphatic System Cancer 2 46.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SMO is a transmembrane protein that localizes to the cell membrane when hedgehog (Hh) ligands (Sonic, Indian, or Desert Hh) bind to cell surface receptor Patched1 (Ptch1).
Ptch1 Binding (bind) of SMO
1) Confidence 0.25 Published 2008 Journal J Hematol Oncol Section Body Doc Link PMC2647552 Disease Relevance 0.65 Pain Relevance 0.05
SMO is a transmembrane protein that localizes to the cell membrane when hedgehog (Hh) ligands (Sonic, Indian, or Desert Hh) bind to cell surface receptor Patched1 (Ptch1).
Patched1 Binding (bind) of SMO
2) Confidence 0.25 Published 2008 Journal J Hematol Oncol Section Body Doc Link PMC2647552 Disease Relevance 0.64 Pain Relevance 0.05

General Comments

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