INT262756

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Context Info
Confidence 0.31
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.55
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

DNA binding (STAT3, NFE2L2) cytoplasm (STAT3, NFE2L2) cytosol (STAT3, NFE2L2)
nucleus (STAT3, NFE2L2) plasma membrane (STAT3, NFE2L2) nucleoplasm (STAT3)
STAT3 (Homo sapiens)
NFE2L2 (Homo sapiens)
Pain Link Frequency Relevance Heat
peripheral neuropathy 2 30.08 Quite Low
headache 4 5.00 Very Low Very Low Very Low
positron emission tomography 4 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 38 97.00 Very High Very High Very High
Thyroid Neoplasm 2 96.24 Very High Very High Very High
Disease 14 94.80 High High
Skin Cancer 11 94.52 High High
Leukocytosis 1 92.32 High High
Thrombosis Related Under Development 1 90.96 High High
Mantle-cell Lymphoma 1 85.04 High High
Pancreatic Cancer 3 80.56 Quite High
Diarrhoea 6 71.28 Quite High
Appetite Loss 4 70.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
B, STAT3 and their target cyclin D1 levels, as well as induction of Nrf2.
STAT3 Positive_regulation (induction) of Nrf2
1) Confidence 0.31 Published 2008 Journal J Hematol Oncol Section Body Doc Link PMC2647552 Disease Relevance 1.55 Pain Relevance 0

General Comments

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