INT262775

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Context Info
Confidence 0.28
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.10
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PIK3CG) plasma membrane (PIK3CG) cytoplasm (PIK3CG)
Anatomy Link Frequency
skin 3
Hair 1
PIK3CG (Homo sapiens)
Pain Link Frequency Relevance Heat
positron emission tomography 8 87.52 High High
headache 8 5.00 Very Low Very Low Very Low
peripheral neuropathy 4 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Bioavailability 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 76 99.66 Very High Very High Very High
Gastrointestinal Neoplasms 2 68.40 Quite High
Toxicity 16 55.56 Quite High
Disease 28 38.48 Quite Low
Colon Cancer 12 30.24 Quite Low
Skin Cancer 22 28.72 Quite Low
Reprotox - General 1 4 25.68 Quite Low
Fatigue 18 5.00 Very Low Very Low Very Low
Vomiting 12 5.00 Very Low Very Low Very Low
Solid Tumor 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Hair, skin, and tumor biopsies showed decreased phosphorylation of many products downstream from the PI3K/mTOR pathway inhibited by XL765.
Negative_regulation (decreased) of Phosphorylation (phosphorylation) of PI3K in skin associated with cancer
1) Confidence 0.28 Published 2008 Journal J Hematol Oncol Section Body Doc Link PMC2647552 Disease Relevance 0.55 Pain Relevance 0.04
Hair, skin, and tumor biopsies showed decreased phosphorylation of many products downstream from the PI3K/mTOR pathway inhibited by XL765.
Negative_regulation (decreased) of in Hair Phosphorylation (phosphorylation) of PI3K in skin associated with cancer
2) Confidence 0.09 Published 2008 Journal J Hematol Oncol Section Body Doc Link PMC2647552 Disease Relevance 0.55 Pain Relevance 0.04

General Comments

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