INT2628

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Context Info
Confidence 0.13
First Reported 1979
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 4.22
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Shbg) extracellular region (Shbg)
Anatomy Link Frequency
blood 4
blood vessel 2
Shbg (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Calcium channel 12 79.12 Quite High
tetrodotoxin 1 78.76 Quite High
addiction 2 76.20 Quite High
Serotonin 1 75.00 Quite High
cva 9 51.52 Quite High
anesthesia 11 5.00 Very Low Very Low Very Low
ischemia 10 5.00 Very Low Very Low Very Low
headache 6 5.00 Very Low Very Low Very Low
beta blocker 5 5.00 Very Low Very Low Very Low
Onset of action 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Emergencies 20 99.72 Very High Very High Very High
Stress 4 99.56 Very High Very High Very High
Hypertension 204 99.52 Very High Very High Very High
Fatigue 1 99.12 Very High Very High Very High
Atherosclerosis 2 95.32 Very High Very High Very High
Pressure And Volume Under Development 96 93.40 High High
Rupture 1 92.68 High High
Increased Venous Pressure Under Development 5 91.96 High High
Aging 7 87.68 High High
Aggression 2 76.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Nevertheless, the elevation of SBP increases the sheer stress and fatigue on arterial walls, accelerating arterial damage, exacerbating the arterial changes and atherosclerosis, creating a vicious cycle of plaque formation and rupture, further blood vessel damage, and loss of arterial distensibility.
Positive_regulation (increases) of Localization (elevation) of SBP in blood vessel associated with stress, rupture, atherosclerosis and fatigue
1) Confidence 0.13 Published 2008 Journal Current Cardiology Reviews Section Body Doc Link PMC2774582 Disease Relevance 1.21 Pain Relevance 0
A marked increase in SBP (but not LDH) release was provoked by electrical field stimulation at 10 Hz, and this increased release (but not the spontaneous release) was Ca2+-dependent.
Positive_regulation (increase) of Localization (release) of SBP
2) Confidence 0.08 Published 1979 Journal Brain Res. Section Abstract Doc Link 487123 Disease Relevance 0.09 Pain Relevance 0.19
The Seventh Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure11 defined a ‘hypertensive emergency’ as an acute elevation in systolic blood pressure (SBP) and diastolic blood pressure (DBP) associated with end-organ damage; while an acute elevation of SBP and/or DBP without end-organ damage can be defined as a ‘hypertensive urgency’.11
Positive_regulation (elevation) of Localization (elevation) of SBP in blood associated with emergencies and hypertension
3) Confidence 0.03 Published 2009 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2724192 Disease Relevance 1.46 Pain Relevance 0.07
The Seventh Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure11 defined a ‘hypertensive emergency’ as an acute elevation in systolic blood pressure (SBP) and diastolic blood pressure (DBP) associated with end-organ damage; while an acute elevation of SBP and/or DBP without end-organ damage can be defined as a ‘hypertensive urgency’.11
Positive_regulation (elevation) of Localization (elevation) of SBP in blood associated with emergencies and hypertension
4) Confidence 0.02 Published 2009 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2724192 Disease Relevance 1.45 Pain Relevance 0.07

General Comments

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