INT262817

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Context Info
Confidence 0.06
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.30
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Serpinf1) extracellular region (Serpinf1) cytoskeleton (1190002H23Rik)
nucleus (1190002H23Rik) cell cycle (1190002H23Rik) cytoplasm (1190002H23Rik)
Serpinf1 (Mus musculus)
1190002H23Rik (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 17 96.32 Very High Very High Very High
ischemia 3 87.52 High High
cytokine 2 67.68 Quite High
ketamine 2 5.00 Very Low Very Low Very Low
Multiple sclerosis 2 5.00 Very Low Very Low Very Low
Glutamate 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
glial activation 1 5.00 Very Low Very Low Very Low
Inflammatory marker 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Glaucoma 37 98.80 Very High Very High Very High
INFLAMMATION 19 96.32 Very High Very High Very High
Death 9 89.68 High High
Cv Unclassified Under Development 2 87.52 High High
Hypoxia 1 76.04 Quite High
Diabetes Mellitus 2 68.68 Quite High
Diabetic Retinopathy 3 64.68 Quite High
Aging 1 60.48 Quite High
Ocular Hypertension 8 22.72 Low Low
Injury 3 11.80 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The studies reported herein strongly suggest a role for PEDF in the maintenance of RGC in the DBA/2J mouse model of glaucoma, and add indirectly to the evidence for reduced PEDF as a possible pathogenic mechanism in human glaucoma.
PEDF Regulation (role) of Positive_regulation (maintenance) of RGC associated with glaucoma
1) Confidence 0.06 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2647972 Disease Relevance 1.30 Pain Relevance 0.22

General Comments

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