INT262824

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.39
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 1.56
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Serpinf1, Il18) extracellular region (Serpinf1, Il18) cytoplasm (Il18)
Anatomy Link Frequency
retina 6
optic nerve 6
Serpinf1 (Mus musculus)
Il18 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 68 94.24 High High
ischemia 12 5.00 Very Low Very Low Very Low
cytokine 8 5.00 Very Low Very Low Very Low
ketamine 8 5.00 Very Low Very Low Very Low
Multiple sclerosis 8 5.00 Very Low Very Low Very Low
Glutamate 8 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
withdrawal 4 5.00 Very Low Very Low Very Low
glial activation 4 5.00 Very Low Very Low Very Low
Inflammatory marker 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Necrosis 8 94.96 High High
Cancer 8 94.60 High High
INFLAMMATION 76 94.24 High High
Glaucoma 148 66.72 Quite High
Death 36 51.60 Quite High
Ganglion Cysts 36 50.92 Quite High
Blindness 8 47.68 Quite Low
Ocular Hypertension 32 16.72 Low Low
Injury 12 5.00 Very Low Very Low Very Low
Diabetic Retinopathy 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Intravitreal PEDF transfection in DBS/2J mice reduced loss of RGC and nerve fiber layer, delayed vision loss, and reduced TNF, IL-18, and GFAP expression in the retina and optic nerve.


Gene_expression (transfection) of PEDF in optic nerve Negative_regulation (reduced) of Gene_expression (expression) of IL-18 in optic nerve
1) Confidence 0.39 Published 2009 Journal Molecular Vision Section Abstract Doc Link PMC2647972 Disease Relevance 0.63 Pain Relevance 0.11
Ocular PEDF transfection reduces TNF and IL-18 expression in retina and optic nerve of DBA/2J mice
Gene_expression (transfection) of PEDF in retina Negative_regulation (reduces) of Gene_expression (expression) of IL-18 in retina
2) Confidence 0.39 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2647972 Disease Relevance 0.15 Pain Relevance 0.07
Ocular PEDF transfection reduces TNF and IL-18 expression in retina and optic nerve of DBA/2J mice
Gene_expression (transfection) of PEDF in retina Negative_regulation (reduces) of in optic nerve Gene_expression (expression) of IL-18 in retina
3) Confidence 0.13 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2647972 Disease Relevance 0.15 Pain Relevance 0.07
Intravitreal PEDF transfection in DBS/2J mice reduced loss of RGC and nerve fiber layer, delayed vision loss, and reduced TNF, IL-18, and GFAP expression in the retina and optic nerve.


Gene_expression (transfection) of PEDF in optic nerve Negative_regulation (reduced) of in retina Gene_expression (expression) of IL-18 in optic nerve
4) Confidence 0.13 Published 2009 Journal Molecular Vision Section Abstract Doc Link PMC2647972 Disease Relevance 0.63 Pain Relevance 0.11

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox