INT262876

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Context Info
Confidence 0.16
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.41
Pain Relevance 1.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein modification process (ST8SIA2) Golgi apparatus (ST8SIA2) carbohydrate metabolic process (ST8SIA2)
Anatomy Link Frequency
joint 1
ST8SIA2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 6 98.68 Very High Very High Very High
Pain 4 96.36 Very High Very High Very High
Sciatic nerve 2 93.76 High High
dexamethasone 2 91.48 High High
anesthesia 2 85.64 High High
Piles 8 82.40 Quite High
Spinal cord 2 81.08 Quite High
Lasting pain 2 80.48 Quite High
Ziconotide 4 76.36 Quite High
conotoxin 4 68.96 Quite High
Disease Link Frequency Relevance Heat
Toxicity 24 99.24 Very High Very High Very High
INFLAMMATION 5 98.68 Very High Very High Very High
Pain 4 96.36 Very High Very High Very High
Arthralgia 2 95.72 Very High Very High Very High
Anorectal Disorders 8 82.40 Quite High
Frailty 2 81.36 Quite High
Diarrhoea 39 75.20 Quite High
Infection 25 71.28 Quite High
Sprains And Strains 50 61.36 Quite High
Hemolytic Uremic Syndrome 8 42.96 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The use of STX as a slow release, prolonged anesthetic was recently demonstrated using a novel controlled release system in male Sprague-Dawley rats [150].
Localization (release) of STX
1) Confidence 0.16 Published 2010 Journal Marine Drugs Section Body Doc Link PMC2920551 Disease Relevance 0.44 Pain Relevance 0.65
Liposome formulations of STX for slow and site-directed release for prolonged anaesthesia have since been postulated as a putative treatment of localized pain and severe joint pain [151].
Localization (release) of STX in joint associated with pain and arthralgia
2) Confidence 0.15 Published 2010 Journal Marine Drugs Section Body Doc Link PMC2920551 Disease Relevance 0.66 Pain Relevance 0.74
caused by systemic release of Stx.


Localization (release) of Stx
3) Confidence 0.05 Published 2008 Journal Interdisciplinary Perspectives on Infectious Diseases Section Body Doc Link PMC2648624 Disease Relevance 0.31 Pain Relevance 0

General Comments

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