INT262911

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Context Info
Confidence 0.65
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.93
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL20) extracellular region (IL20)
Anatomy Link Frequency
Th17 1
IL20 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 59 90.00 High High
cytokine 45 82.52 Quite High
psoriasis 25 76.44 Quite High
Inflammatory mediators 4 68.12 Quite High
chemokine 7 55.20 Quite High
Inflammatory response 15 23.20 Low Low
depression 6 5.00 Very Low Very Low Very Low
Neurotransmitter 6 5.00 Very Low Very Low Very Low
Central nervous system 3 5.00 Very Low Very Low Very Low
fluoxetine 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Depression 144 99.12 Very High Very High Very High
Disease 35 97.24 Very High Very High Very High
Psoriasis 43 94.16 High High
INFLAMMATION 76 90.00 High High
Necrosis 4 86.08 High High
Cancer 5 85.72 High High
Anxiety Disorder 9 57.28 Quite High
Panic Disorder 3 54.84 Quite High
Dermatitis 31 46.00 Quite Low
Contact Dermatitis 9 35.08 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Haplotype analysis of the IL10, IL19, IL20, and IL24 genes was performed according to the pairwise linkage disequilibrium pattern observed within each of these genes (cases + controls, n = 429).
Gene_expression (analysis) of IL20
1) Confidence 0.65 Published 2008 Journal BMC Med Genet Section Body Doc Link PMC2648955 Disease Relevance 0.28 Pain Relevance 0
The selected SNPs of block 1 were rs2243188 and rs2243193 of IL19 (intron 6, 3' UTR) and rs2981572 of IL20 (5' near gene) and SNPs of block 2 were rs1518108 of IL20 (3' UTR), rs1150253 and rs1150258 of IL24 (intron 2, exon 5).
Gene_expression (rs1518108) of IL20
2) Confidence 0.65 Published 2008 Journal BMC Med Genet Section Body Doc Link PMC2648955 Disease Relevance 0.26 Pain Relevance 0
The selected SNPs of block 1 were rs2243188 and rs2243193 of IL19 (intron 6, 3' UTR) and rs2981572 of IL20 (5' near gene) and SNPs of block 2 were rs1518108 of IL20 (3' UTR), rs1150253 and rs1150258 of IL24 (intron 2, exon 5).
Gene_expression (rs2981572) of IL20
3) Confidence 0.56 Published 2008 Journal BMC Med Genet Section Body Doc Link PMC2648955 Disease Relevance 0.33 Pain Relevance 0
Importantly, TIP-DC can also produce IL-20 and IL-23, and stimulate the differentiation and activation of IL-17-producing helper T cells (Th17) [20].
Gene_expression (produce) of IL-20 in Th17
4) Confidence 0.24 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2929514 Disease Relevance 1.06 Pain Relevance 0.36

General Comments

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