INT262940

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Context Info
Confidence 0.16
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.91
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (PAX6, SIX3) cell differentiation (PAX6) nucleolus (PAX6)
DNA binding (PAX6) transcription factor binding (PAX6) cytoplasm (PAX6)
Anatomy Link Frequency
lens placode 2
PAX6 (Homo sapiens)
SIX3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Central nervous system 3 21.60 Low Low
imagery 9 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cataract 16 84.24 Quite High
Nystagmus 10 77.80 Quite High
Cerebellar Diseases 9 71.28 Quite High
Congenital Anomalies 21 70.60 Quite High
Congenital Nystagmus 1 67.16 Quite High
Syndrome 5 63.64 Quite High
Cognitive Disorder 10 60.72 Quite High
Epilepsy 6 50.80 Quite High
Intellectual Impairment 6 35.84 Quite Low
Nervous System Malformation 2 20.96 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Indeed, PAX6 has fundamental roles in the developing lens since the earliest stages of its formation as demonstrated by a recent elegant work showing the crucial importance of PAX6 interactions with transcription factors such as SIX3 and SOX2 in the induction of the lens placode [27].
Regulation (importance) of PAX6 Binding (interactions) of SIX3 in lens placode
1) Confidence 0.16 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2649307 Disease Relevance 0.91 Pain Relevance 0

General Comments

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